Season 2

01 A Son in the Oven
43mWatson and the fellows spring back into action when Mary’s mother accidentally poisons herself while suffering from a rare form of dementia that is progressing with impossible speed. Meanwhile, Sherlock Holmes resurfaces after being presumed dead.
2025-10-13 1.8
02 Back from the Dead
43mA microbiology researcher returns from an expedition to Siberia, leading to a possible outbreak of a revived pathogen. Watson reconnects with Sherlock Holmes.
2025-10-20 1.8
03 Expletive Deleted
43mWatson and the team work alongside Laila to help a patient named Maxine, a 30-year-old who looks 10 years old.
2025-10-27 1.9
04 Happy When It Rains
43mWatson and the team jump into action when four new patients are brought to UHOP with wounds that appear to be infected with a flesh-eating bacterium following a tornado. Meanwhile, Shinwell searches for meaning as a nursing student and Adam’s wedding to Lauren risks being halted.
2025-11-03 1.8
05 Lucky
43mWhile visiting another hospital, Watson becomes convinced that a coma patient is suffering from locked-in syndrome and has been mistaken for a coma patient for over a decade. After the patient is transferred to UHOP for treatment, he shocks the team with chilling messages. Meanwhile, Sherlock is back in town and is staying with Watson.
2025-11-10 2.4
06 Buying Time
43mWatson and the fellows race against time to save the life of Xavier, a 21-year-old athlete with a fast-growing, seemingly incurable cancer. Meanwhile, Mycroft Holmes lets Watson know his team’s work at UHOP may no longer have funding available.
2025-11-17 2.8
07 Giant Steps
43mWatson's father, Hamish, visits UHOP to introduce Watson and the fellows to his protégé, Annabelle, a saxophone prodigy with musically induced blackouts. As Annabelle's condition worsens, Watson must confront his long-standing tensions with his father in order to save her.
2025-11-24 2.2
08 Livvy Sees the Doctor
43mUHOP veers into terror when Watson and the fellows are taken hostage by a man with a bomb strapped to his chest who is desperate to find a cure for his 9-year-old daughter’s illness.
2025-12-01 2.0
09 Shannon Says Bex Loves Micah
43mWatson and the fellows help Laila’s son Micah – who was injured in a car accident while pursuing his crush, Bex, with the help of his AI chatbot.
2025-12-08 1.6
10 Never Been CRISPR'd
43mWatson’s biohacker friend Hobie returns when he rushes his new girlfriend to the Holmes Clinic after they partake in a gene-editing experiment that goes wrong. Meanwhile, Watson becomes suspicious of Sherlock.
2025-12-15 1.5
11 The Tunnel Under the Elms
43mWatson and the fellows race against the clock to save a man and his pregnant wife from a terrifying sinkhole. Meanwhile, Ingrid’s future with her therapy group becomes unclear.
2026-03-01 1.9
12 A Family Meal
43mWhen a patient arrives at the Holmes Clinic plagued by a mysterious neurological disorder, Watson and the fellows discover they were forced to eat their parents amid a childhood survival incident. Meanwhile, Adam is struggling with how his future will change as a father.
2026-03-08 3.5
13 For a Limited Time Only
43mWatson and the fellows fight to revive a 30-year-old woman, Audrey, after her heart inexplicably stops repeatedly until they discover she has a rare phenomenon called Lazarus syndrome. As these revivals continue, she uses the short window of time available to right her greatest wrong.
2026-03-15 2.5
14 Wrongful Life
43mWatson is sued for Wrongful Life by a long-term patient suffering from VACTERL association, after undergoing multiple painful surgeries.
2026-03-22 3.0
15 A Third Act Surprise
43mWatson and the fellows race to save the life of a young woman who needs a lifesaving kidney donation. Meanwhile, Sherlock returns to help crack unsolved cases in Pittsburgh.
2026-03-29 2.9
16 Respect the Process. Respect the Quirks
43mWatson investigates a case involving a mentally unstable mother, with the woman's delusions serving as a mirror to his own newly discovered hallucinations.
2026-04-05 3.1
17 Unsolved Mysteries
43mIn the wake of the car accident, Watson and Laila lie injured and awaiting rescue as the team races to find them before it’s too late. Meanwhile, in a state between life and death, Watson’s mind plays out a modern-day investigation of a case that has long haunted him.
2026-04-12 3.5
18 Sic Semper Tyrannis
43mFollowing his brain tumor diagnosis, Watson goes on medical leave to seek treatment, leaving Mary in charge of The Holmes Clinic as a notorious South American dictator demands Watson see to his mysterious autoimmune condition personally. Meanwhile, Ingrid grows more concerned about Beck’s obsession with Sasha.
2026-04-19 3.6
19 Rule of Three
43mAs Adam's wife goes in for a C-section to deliver triplets, chaos ensues when their OB-GYN passes out in the operating room. Meanwhile, a severe storm detours Watson and Mary's trip to find a renowned doctor to remove Watson's brain tumor.
2026-04-26 3.1
20 The Cobalt Fissure
44mA seemingly random murder outside of UHOP sets the stage for the arrival of someone from Watson and Sherlock Holmes' past.
2026-05-03 4.3







